Found 26 matching trials
Efficacy and Safety of Obeticholic Acid in the Treatment of Primary Biliary Cholangitis PHASE3 Obecholic acid is a modified bile acid and Farnesoid X receptor (FXR) agoni...
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Beijing Friendship Hospital
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Effect of Obeticholic Acid on Transport of Bile Acids in PBC Examined by 11C-cholyl-sarcosine PET/CT EARLY_PHASE1 This is an investigator-initiated, double-blind crossover study on the mech...
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Effect of Heavy Alcohol Consumption on Farnesoid X Receptor (FXR) Signaling NA The main purpose of this study is to see whether heavy drinking will interf...
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Indiana University
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Phase 3 Study of Obeticholic Acid in Patients With Primary Biliary Cirrhosis PHASE3 The main objectives of the study were to assess the effects of Obeticholic ...
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UC Davis Medical Center
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Study to Assess Efficacy, Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of Obeticholic Acid (OCA) Compared to Placebo in Pediatric Participants With Biliary Atresia, Post-hepatoportoenterostomy PHASE2 This study will evaluate the efficacy, safety and tolerability, as well as ...
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Queensland Childrens Hospital
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Obeticholic Acid (OCA) in Primary Sclerosing Cholangitis (PSC) PHASE2 This was a phase 2, double-blind (DB), placebo-controlled trial in particip...
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St. Joseph's Hospital & Medical Center
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Study of OCA in Combination With BZF Evaluating Efficacy, Safety and Tolerability in Participants With PBC PHASE2 Study to determine the effect of the investigational drug bezafibrate (BZF)...
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University of Alabama at Birmingham
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Study of INT-747 as Monotherapy in Participants With Primary Biliary Cirrhosis (PBC) PHASE2 The primary hypothesis was that obeticholic acid (OCA) will cause a reducti...
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Phase 4 Study of Obeticholic Acid Evaluating Clinical Outcomes in Patients With Primary Biliary Cholangitis PHASE4 Primary Biliary Cholangitis (PBC) is a serious, life-threatening, bile acid...
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Mayo Clinic Arizona
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The Farnesoid X Receptor (FXR) Ligand Obeticholic Acid in NASH Treatment Trial(FLINT) PHASE2 Administration of the farnesoid X receptor (FXR) ligand obeticholic acid (O...
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University of California, San Diego
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